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5 Causes of Colon Cancer

Hadeel Ahmed

08 Oct 2026

43

Colon cancer is one of the most common types of cancer worldwide. It is the third most common cancer globally, with around 2 million new cases and nearly 1 million deaths recorded in 2022.

Colorectal cancer affects the large intestine, including the colon and rectum. The risk of developing the disease increases among people over the age of 50, and it can often be fatal.

The highest incidence rates are found in high income countries, particularly in Europe, the United States, Australia, Japan, and New Zealand.

In the Middle East and North Africa, colorectal cancer incidence rates range from 15 to 36 cases per 100,000 people.

Symptoms may include changes in bowel habits, such as diarrhea or constipation, changes in stool consistency, rectal bleeding or blood in the stool, abdominal pain, and persistent bloating.

A study published in The Lancet Gastroenterology & Hepatology suggests that an experimental blood test may enable the early detection of colorectal cancer and help prevent the disease by identifying high risk polyps before they develop into cancerous tumors.

Because prevention is better than cure, here are five major risk factors associated with colorectal cancer:

First: Fast food and ready made meals

According to a recent study published in GUT, an international medical journal, the ongoing harmful effects of fast food and ready made meals may increase the risk of developing colorectal tumors.

Second: Fried foods and soft drinks

A study examining colorectal cancer cells found that a diet high in fried foods and soft drinks may contribute to the growth of cancerous cells.

Third: A diet high in saturated fat and low in fiber

Doctors and specialists say that excessive consumption of foods rich in saturated fats and low in fiber can increase the production of primary bile acids and lead to their accumulation in the colon. Gut bacteria then convert them into secondary bile acids, particularly deoxycholic acid, which has been found at elevated levels in stool samples from people with colorectal cancer.

Fourth: Red meat

A study published in Nature that examined the effects of 97 dietary factors on human health found that red meat consumption was associated with a higher risk of colorectal cancer, while the consumption of fruits, whole grains, and fiber was associated with a lower risk.

Fifth: Smoking, alcohol, and obesity

Colorectal cancer rates have been rising among people under the age of 50. Recent studies have linked this increase to factors including smoking, alcohol consumption, and obesity.

To help reduce the risk of colorectal cancer, experts recommend quitting smoking, maintaining a healthy weight, limiting fat intake, exercising regularly, eating plenty of fruits and vegetables, following a healthy diet, and avoiding fast food.

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